September 9th, 2026 - Press notes
This technique identifies tumour mutations for which treatments are available, showing a high level of concordance with the analysis of tumour tissue samples.
This makes it a particularly useful alternative when there is insufficient tissue available to carry out comprehensive molecular profiling of the tumour.
Published in Clinical Cancer Research, the study analyses the largest cohort described to date, comprising nearly 11,000 patients, and validates the findings in an independent cohort of 126 patients with biliary tract cancer from nine hospitals across Spain.
July 28th, 2026 - Press release
The initiative is part of MENTBEST, a European mental health research project that proposes evidence-based community interventions and innovative technologies to prevent and mitigate mental health problems across Europe.
Focused on depression prevention, the app monitors users' daily activity, asks specific questions and provides recommendations tailored to their needs. A multicentre clinical trial is currently under way to assess its functionality.
Its content has been developed by a team of expert psychologists and psychiatrists, and it is the only app of its kind currently undergoing the process required to obtain certification as a medical device. It is being evaluated through a clinical trial that is currently recruiting volunteers.
July 14 th, 2026 - Press notes
People who experienced traumatic events during childhood are 1.5 times more likely to develop physical illnesses than the general population.
The association is strongest in cases of bullying, physical or sexual abuse, and parental loss or abandonment, according to a study led by the Hospital del Mar Research Institute that analyzed data from 250 published studies on the subject up to April 2025.
The findings may help draw attention to the possible causes of a wide range of physical diseases and reinforce efforts to prevent childhood trauma.
July 9th, 2026 - Press notes
Hospital del Mar Research Institute is participating in this European project, which aims to advance knowledge of the functions of the proteins that make up the so-called dark proteome. Led by the Princess Máxima Center for Pediatric Oncology in the Netherlands, it will train fifteen PhD students, who will focus their research on this field.
June 18, 2026 - Press release
A study in mice by the Hospital del Mar Research Institute and the IIBB-CSIC, published in Science Advances, identifies inhibition of the PARP2 protein as a therapeutic target for treating pancreatic cancer, the third leading cause of cancer death worldwide.
The study analyses the role of this protein in tumour development and protection, and describes how its elimination leads to tumour cell death and activation of the immune System.
Specifically blocking this protein may be a useful strategy for treating a large number of patients with pancreatic cancer and could even be applicable to other types of tumours.
May 19th, 2026 - Press release
An international study involving researchers from the Hospital del Mar Research Institute reveals a key interaction between two proteins that are fundamental in tumour development.
To achieve this, molecular modelling and artificial intelligence techniques were used, revealing for the first time a new structural model that describes a previously unknown cell-signalling mechanism.
The research opens the door to designing drugs that act on the interaction between the two proteins, thereby improving current cancer treatments.
May 18th, 2026 - Press notes
An international study published in the journal Nature has designated a subset of the so-called dark proteins - proteins with no known function - as peptideins. Characterising them opens the door to studying them and analysing their functions.
May 12th, 2026 - Press notes
In an article published in the journal Neuron, Dr. Rodrigo Quian Quiroga proposes that the way we organize our memories constitutes the mechanism that gives rise to human intelligence.
The human brain generates memories from the representation of the stimuli it receives, endowing them with meaning. This is a mechanism of abstraction that does not merely store information.
Published scientific evidence indicates that this mechanism is not found in other animal species, suggesting that it is a key element in the construction of our intelligence.
May 8th, 2026 - Press release
An international collaborative study, published in the Journal of Experimental Medicine, highlights the role of immunoglobulin D (IgD) in the processes involved in generating tolerance to antigens and bacteria that live in our body.
The study characterizes, for the first time, the cells that produce these antibodies and identifies their point of origin in the tonsils.
These results open the door to the possibility of developing drugs and vaccines focused on this type of antibody, both for the treatment of allergies and other diseases linked to inflammation.
April 14, 2026 - Press release
At present, only around 5% of patients with colon cancer are candidates for immunotherapy. This new biomarker could make it possible to determine more accurately which individuals may receive this treatment with a likelihood of success and expand the number of patients who could benefit from it.
The study, led by the Hospital del Mar Research Institute and IRB Barcelona, shows that the determination of this protein, CTHRC1, can be used to assess patient prognosis. At the same time, it opens up new avenues to approach this type of tumour.
The research team has demonstrated that this biomarker can be detected using routine diagnostic tests in the clinical practice of any Pathology service.
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